| Active Roster | ||||||||
|---|---|---|---|---|---|---|---|---|
| Name | No. | Pos. | Ht. | Wt. | Age | Exp. | League Entry | College |
| Addai, Joseph | 29 | RB | 5-11 | 214 | 28 | 6 | D1 30th (Colts-06) | LSU Tigers |
| Addison, Mario | 97 | DE | 6-03 | 252 | 24 | R | UDFA (Bears-11) | Troy State Trojans |
| Anderson, Jamaal | 90 | DE | 6-05 | 288 | 25 | 5 | D1 8th (Falcons-07) | Arkansas Razorbacks |
| Angerer, Pat | 51 | ILB | 6-00 | 235 | 25 | 2 | D2 63rd (Colts-10) | Iowa Hawkeyes |
| Bentley, Kevin | 57 | OLB | 6-00 | 248 | 32 | 10 | D4 101st (Browns-02) | Northwestern Wildcats |
| Bethea, Antoine | 41 | S | 5-11 | 203 | 27 | 6 | D6 207th (Colts-06) | Howard Bison |
| Brayton, Tyler | 96 | DE | 6-06 | 280 | 32 | 9 | D1 32nd (Raiders-03) | Colorado Buffaloes |
| Brown, Donald | 31 | RB | 5-10 | 210 | 24 | 3 | D1 27th (Colts-09) | Connecticut Huskies |
| Caldwell, David | 30 | S | 5-11 | 212 | 24 | 1 | UDFA (Colts-10) | William & Mary Tribe |
| Carter, Delone | 34 | RB | 5-09 | 225 | 24 | R | D4 119th (Colts-11) | Syracuse Orangemen |
| Castonzo, Anthony | 74 | OT | 6-07 | 311 | 23 | R | D1 22nd (Colts-11) | Boston College Eagles |
| Clark, Dallas | 44 | TE | 6-03 | 252 | 32 | 9 | D1 24th (Colts-03) | Iowa Hawkeyes |
| Collie, Austin | 17 | WR | 6-00 | 200 | 26 | 3 | D4 127th (Colts-09) | BYU Cougars |
| Conner, Kavell | 53 | OLB | 6-00 | 242 | 24 | 2 | D7 240th (Colts-10) | Clemson Tigers |
| Cosby, Quan | 17 | WR | 5-09 | 196 | 29 | 3 | UDFA (Bengals-09) | Texas Longhorns |
| Diem, Ryan | 71 | OG | 6-06 | 320 | 32 | 11 | D4 118th (Colts-01) | Northern Illinois Huskies |
| Diles, Zach | 53 | OLB | 6-00 | 240 | 26 | 5 | D7 218th (Texans-07) | Kansas State Wildcats |
| Edds, A.J. | 52 | ILB | 6-04 | 244 | 24 | 2 | D4 119th (Dolphins-10) | Iowa Hawkeyes |
| Eldridge, Brody | 81 | TE | 6-05 | 265 | 24 | 2 | D5 162nd (Colts-10) | Oklahoma Sooners |
| Felton, Jerome | 42 | FB | 6-00 | 246 | 25 | 4 | D5 146th (Lions-08) | Furman Paladins |
| Freeney, Dwight | 93 | DE | 6-01 | 268 | 31 | 10 | D1 11th (Colts-02) | Syracuse Orangemen |
| Garcon, Pierre | 85 | WR | 6-00 | 210 | 26 | 4 | D6 205th (Colts-08) | Mount Union Purple Raiders |
| Gonzalez, Anthony | 11 | WR | 6-00 | 193 | 27 | 5 | D1 32nd (Colts-07) | Ohio State Buckeyes |
| Hill, Anthony | 83 | TE | 6-06 | 278 | 27 | 3 | D4 122nd (Texans-09) | North Carolina State Wolfpack |
| Hines, Jermale | 26 | S | 6-01 | 218 | 24 | R | D5 158th (Rams-11) | Ohio State Buckeyes |
| Holmes, Michael | 20 | CB | 5-11 | 184 | 22 | R | UDFA (Bears-11) | Syracuse Orangemen |
| Hughes, Jerry | 92 | DE | 6-02 | 255 | 23 | 2 | D1 31st (Colts-10) | TCU Horned Frogs |
| Johnson, Antonio | 99 | DT | 6-03 | 310 | 27 | 5 | D5 152nd (Titans-07) | Mississippi State Bulldogs |
| King, Brandon | 37 | CB | 5-10 | 194 | 25 | 2 | UDFA (Colts-10) | Purdue Boilermakers |
| Lacey, Jacob | 27 | CB | 5-10 | 177 | 24 | 3 | UDFA (Colts-09) | Oklahoma State Cowboys |
| Lefeged, Joe | 35 | S | 6-00 | 205 | 23 | R | UDFA (Colts-11) | Rutgers Scarlet Knights |
| Linkenbach, Jeff | 72 | OT | 6-06 | 311 | 24 | 2 | UDFA (Colts-10) | Cincinnati Bearcats |
| Lutrus, Scott | 56 | OLB | 6-02 | 241 | 23 | R | UDFA (Jaguars-11) | Connecticut Huskies |
| Mahaffey, Ryan | 47 | FB | 6-02 | 255 | 24 | R | UDFA (Ravens-11) | Northern Iowa Panthers |
| Manning, Peyton | 18 | QB | 6-05 | 230 | 35 | 14 | D1 1st (Colts-98) | Tennessee Volunteers |
| Mathews, Ricardo | 91 | DT | 6-03 | 294 | 24 | 2 | D7 238th (Colts-10) | Cincinnati Bearcats |
| Mathis, Robert | 98 | DE | 6-02 | 245 | 30 | 9 | D5 138th (Colts-03) | Alabama A&M Bulldogs |
| McAfee, Pat | 1 | P | 6-01 | 220 | 25 | 3 | D7 222nd (Colts-09) | West Virginia Mountaineers |
| Moala, Fili | 95 | DT | 6-04 | 303 | 26 | 3 | D2 56th (Colts-09) | USC Trojans |
| Ojinnaka, Quinn | 69 | OT | 6-05 | 305 | 27 | 6 | D5 139th (Falcons-06) | Syracuse Orangemen |
| Orlovsky, Dan | 6 | QB | 6-05 | 230 | 28 | 7 | D5 145th (Lions-05) | Connecticut Huskies |
| Painter, Curtis | 7 | QB | 6-04 | 230 | 26 | 3 | D6 201st (Colts-09) | Purdue Boilermakers |
| Pollak, Michael | 78 | OG | 6-03 | 301 | 26 | 4 | D2 59th (Colts-08) | Arizona State Sun Devils |
| Reitz, Joe | 76 | OG | 6-07 | 320 | 26 | 1 | UDFA (Ravens-08) | Western Michigan Broncos |
| Richard, Jamey | 61 | OG | 6-05 | 295 | 27 | 4 | D7 236th (Colts-08) | Buffalo Bulls |
| Rucker, Chris | 36 | CB | 6-01 | 195 | 23 | R | D6 188th (Colts-11) | Michigan State Spartans |
| Saturday, Jeff | 63 | C | 6-02 | 295 | 36 | 13 | UDFA (Ravens-98) | North Carolina Tar Heels |
| Sims, Ernie | 55 | OLB | 6-00 | 230 | 27 | 6 | D1 9th (Lions-06) | Florida State Seminoles |
| Snow, Justin | 48 | LS | 6-03 | 240 | 35 | 12 | UDFA (Colts-00) | Baylor Bears |
| Tamme, Jacob | 84 | TE | 6-03 | 236 | 26 | 4 | D4 127th (Colts-08) | Kentucky Wildcats |
| Thomas, Kevin | 21 | CB | 6-00 | 192 | 25 | 2 | D3 94th (Colts-10) | USC Trojans |
| Vinatieri, Adam | 4 | K | 6-00 | 202 | 39 | 16 | UDFA (Patriots-96) | South Dakota State Jackrabbits |
| Wayne, Reggie | 87 | WR | 6-00 | 198 | 33 | 11 | D1 30th (Colts-01) | Miami (Fla.) Hurricanes |
| Injured Reserve | ||||||||
| Name | No. | Pos. | Ht. | Wt. | Age | Exp. | League Entry | College |
| Brackett, Gary | 58 | ILB | 5-11 | 235 | 31 | 9 | UDFA (Colts-03) | Rutgers Scarlet Knights |
| Brown, Stevie | 28 | S | 5-11 | 215 | 24 | 2 | D7 251st (Raiders-10) | Michigan Wolverines |
| Bullitt, Melvin | 33 | S | 6-01 | 201 | 27 | 5 | UDFA (Colts-07) | Texas A&M Aggies |
| Collins, Kerry | 5 | QB | 6-05 | 250 | 39 | 17 | D1 5th (Panthers-95) | Penn State Nittany Lions |
| Foster, Eric | 68 | DT | 6-02 | 265 | 26 | 4 | UDFA (Colts-08) | Rutgers Scarlet Knights |
| Gronkowski, Chris | 49 | FB | 6-02 | 245 | 25 | 2 | UDFA (Cowboys-10) | Arizona Wildcats |
| Ijalana, Benjamin | 79 | OT | 6-04 | 317 | 22 | R | D2 49th (Colts-11) | Villanova Wildcats |
| Johnson, Terrence | 23 | CB | 5-09 | 190 | 25 | 1 | UDFA (Patriots-10) | California (Pa.) Vulcans |
| Nevis, Drake | 94 | DT | 6-01 | 294 | 22 | R | D3 87th (Colts-11) | LSU Tigers |
| Olsen, Seth | 73 | OG | 6-04 | 306 | 26 | 2 | D4 132nd (Broncos-09) | Iowa Hawkeyes |
| Powers, Jerraud | 25 | CB | 5-10 | 192 | 24 | 3 | D3 92nd (Colts-09) | Auburn Tigers |
| Thomas, Jaimie | 73 | OG | 6-04 | 330 | 25 | 2 | D7 236th (Colts-09) | Maryland Terrapins |
| Wheeler, Philip | 50 | OLB | 6-02 | 240 | 27 | 4 | D3 93rd (Colts-08) | Georgia Tech Yellow Jackets |
| White, Blair | 15 | WR | 6-02 | 205 | 24 | 2 | UDFA (Colts-10) | Michigan State Spartans |
| Williams, James | 60 | OT | 6-05 | 295 | 25 | 1 | UDFA (Buccaneers-10) | Harvard Crimson |
| Reserve - Future | ||||||||
| Name | No. | Pos. | Ht. | Wt. | Age | Exp. | League Entry | College |
| Evans, Darren | 32 | RB | 6-00 | 220 | 23 | R | UDFA (Colts-11) | Virginia Tech Hokies |
| Fayson, Jarred | 16 | WR | 6-01 | 215 | 24 | R | UDFA (Saints-11) | Illinois Fighting Illini' |
| Freeman, Jerrell | OLB | 6-00 | 234 | 25 | 1 | UDFA (Titans-08) | Mary Hardin-Baylor Crusaders | |
| Harvey, Mario | ILB | 6-00 | 250 | 24 | R | UDFA (Steelers-11) | Marshall Thundering Herd | |
| Murphy, Matt | 60 | OT | 6-04 | 300 | 22 | R | UDFA (Falcons-11) | UNLV Rebels |
| Ogbu, Ollie | 64 | DT | 6-01 | 283 | 24 | R | UDFA (Colts-11) | Penn State Nittany Lions |
| Ross, Jeremy | 10 | WR | 5-11 | 213 | 23 | R | UDFA (Patriots-11) | California Golden Bears |
| Shipley, A.Q. | C | 6-01 | 315 | 25 | 1 | D7 226th (Steelers-09) | Penn State Nittany Lions | |
| Tepper, Mike | 67 | OT | 6-06 | 323 | 26 | 1 | UDFA (Cowboys-10) | California Golden Bears |