| Active Roster | ||||||||
|---|---|---|---|---|---|---|---|---|
| Name | No. | Pos. | Ht. | Wt. | Age | Exp. | League Entry | College |
| Aiken, Kamar | 88 | WR | 6-02 | 219 | 22 | R | UDFA (Bills-11) | UCF Golden Knights |
| Barnett, Nick | 50 | ILB | 6-02 | 240 | 30 | 9 | D1 29th (Packers-03) | Oregon State Beavers |
| Batten, Danny | 57 | OLB | 6-03 | 254 | 24 | 1 | D6 192nd (Bills-10) | South Dakota State Jackrabbits |
| Bell, Demetrius | 77 | OT | 6-05 | 301 | 27 | 3 | D7 219th (Bills-08) | Northwestern State (La.) Demons |
| Brock, Kevin | 87 | TE | 6-05 | 260 | 25 | 1 | UDFA (Panthers-09) | Rutgers Scarlet Knights |
| Brown, Colin | 74 | OG | 6-07 | 335 | 26 | 1 | D5 139th (Chiefs-09) | Missouri Tigers |
| Byrd, Jairus | 31 | S | 5-10 | 207 | 25 | 3 | D2 42nd (Bills-09) | Oregon Ducks |
| Carrington, Alex | 92 | DE | 6-05 | 285 | 24 | 2 | D3 72nd (Bills-10) | Arkansas State Indians |
| Chandler, Scott | 84 | TE | 6-07 | 265 | 26 | 3 | D4 129th (Chargers-07) | Iowa Hawkeyes |
| Choice, Tashard | 40 | RB | 5-10 | 218 | 27 | 4 | D4 122nd (Cowboys-08) | Georgia Tech Yellow Jackets |
| Corner, Reggie | 27 | CB | 5-10 | 180 | 28 | 4 | D4 114th (Bills-08) | Akron Zips |
| Coutu, Brandon | 10 | K | 5-11 | 188 | 27 | 2 | D7 235th (Seahawks-08) | Georgia Bulldogs |
| Dareus, Marcell | 99 | NT | 6-03 | 319 | 22 | R | D1 3rd (Bills-11) | Alabama Crimson Tide |
| Davis, Andra | 54 | ILB | 6-01 | 250 | 33 | 10 | D5 141st (Browns-02) | Florida Gators |
| Dotson, Lionel | 97 | DE | 6-04 | 296 | 26 | 4 | D7 245th (Dolphins-08) | Arizona Wildcats |
| Edwards, Dwan | 98 | DE | 6-02 | 309 | 30 | 7 | D2 51st (Ravens-04) | Oregon State Beavers |
| Fitzpatrick, Ryan | 14 | QB | 6-02 | 225 | 29 | 7 | D7 250th (Rams-05) | Harvard Crimson |
| Florence, Drayton | 29 | CB | 6-01 | 195 | 31 | 9 | D2 46th (Chargers-03) | Tuskegee Golden Tigers |
| Gilbert, Jarron | 73 | DE | 6-05 | 288 | 25 | 3 | D3 68th (Bears-09) | San Jose State Spartans |
| Hagan, Derek | 80 | WR | 6-02 | 215 | 27 | 5 | D3 82nd (Dolphins-06) | Arizona State Sun Devils |
| Hairston, Chris | 75 | OT | 6-07 | 333 | 22 | R | D4 122nd (Bills-11) | Clemson Tigers |
| Heard, Kellen | 72 | DT | 6-06 | 355 | 26 | 1 | UDFA (Raiders-10) | Memphis Tigers |
| Jasper, Michael | 69 | DT | 6-04 | 394 | 25 | R | D7 245th (Bills-11) | Bethel Wildcats |
| Johnson, Spencer | 91 | OLB | 6-03 | 290 | 30 | 8 | UDFA (Vikings-04) | Auburn Tigers |
| Johnson, Steve | 13 | WR | 6-02 | 210 | 25 | 4 | D7 224th (Bills-08) | Kentucky Wildcats |
| Kelsay, Chris | 90 | OLB | 6-04 | 273 | 32 | 9 | D2 48th (Bills-03) | Nebraska Cornhuskers |
| Levitre, Andy | 67 | OG | 6-02 | 306 | 25 | 3 | D2 51st (Bills-09) | Oregon State Beavers |
| Martin, Ruvell | 82 | WR | 6-04 | 220 | 30 | 6 | UDFA (Chargers-04) | Saginaw Valley State Cardinals |
| McIntyre, Corey | 38 | FB | 6-00 | 258 | 33 | 7 | UDFA (Eagles-02) | West Virginia Mountaineers |
| McKelvin, Leodis | 21 | CB | 5-11 | 187 | 26 | 4 | D1 11th (Bills-08) | Troy State Trojans |
| Moats, Arthur | 52 | OLB | 6-00 | 246 | 23 | 2 | D6 178th (Bills-10) | James Madison Dukes |
| Moore, Kyle | 94 | DE | 6-06 | 272 | 25 | 3 | D4 117th (Buccaneers-09) | USC Trojans |
| Moorman, Brian | 8 | P | 6-00 | 175 | 35 | 11 | UDFA (Seahawks-99) | Pittsburg State Gorillas |
| Morrison, Kirk | 58 | ILB | 6-02 | 240 | 29 | 7 | D3 78th (Raiders-05) | San Diego State Aztecs |
| Nelson, David | 86 | WR | 6-05 | 217 | 25 | 2 | UDFA (Bills-10) | Purdue Boilermakers |
| Nesbitt, Joshua | 47 | S | 6-01 | 217 | 23 | R | UDFA (Bills-11) | Georgia Tech Yellow Jackets |
| Onobun, Fendi | 89 | TE | 6-06 | 249 | 25 | 2 | D6 170th (Rams-10) | Houston Cougars |
| Pears, Erik | 79 | OT | 6-08 | 315 | 29 | 7 | UDFA (Broncos-05) | Colorado State Rams |
| Rinehart, Chad | 76 | OG | 6-05 | 311 | 26 | 4 | D3 96th (Redskins-08) | Northern Iowa Panthers |
| Rogers, Justin | 26 | CB | 5-11 | 183 | 24 | R | D7 206th (Bills-11) | Richmond Spiders |
| Roosevelt, Naaman | 18 | WR | 6-00 | 189 | 24 | 2 | UDFA (Bills-10) | Buffalo Bulls |
| Sanborn, Garrison | 65 | LS | 6-02 | 240 | 26 | 3 | UDFA (Bills-09) | Florida State Seminoles |
| Scott, Bryan | 43 | S | 6-01 | 219 | 30 | 9 | D2 55th (Falcons-03) | Penn State Nittany Lions |
| Searcy, Da’Norris | 25 | S | 6-00 | 210 | 23 | R | D4 100th (Bills-11) | North Carolina Tar Heels |
| Sheppard, Kelvin | 55 | ILB | 6-02 | 250 | 24 | R | D3 68th (Bills-11) | LSU Tigers |
| Smith, Brad | 16 | QB | 6-02 | 212 | 28 | 6 | D4 103rd (Jets-06) | Missouri Tigers |
| Spiller, C.J. | 28 | RB | 5-10 | 196 | 24 | 2 | D1 9th (Bills-10) | Clemson Tigers |
| Thigpen, Tyler | 4 | QB | 6-01 | 224 | 27 | 5 | D7 217th (Vikings-07) | Coastal Carolina Chanticleers |
| Urbik, Kraig | 60 | C | 6-05 | 322 | 26 | 2 | D3 79th (Steelers-09) | Wisconsin Badgers |
| White, Johnny | 20 | RB | 5-10 | 205 | 24 | R | D5 133rd (Bills-11) | North Carolina Tar Heels |
| Williams, Aaron | 23 | CB | 6-01 | 195 | 22 | R | D2 34th (Bills-11) | Texas Longhorns |
| Wilson, George | 37 | S | 6-00 | 212 | 30 | 6 | UDFA (Lions-04) | Arkansas Razorbacks |
| Young, Sam | 71 | OT | 6-08 | 316 | 24 | 2 | D6 179th (Cowboys-10) | Notre Dame Fighting Irish |
| Injured Reserve | ||||||||
| Name | No. | Pos. | Ht. | Wt. | Age | Exp. | League Entry | College |
| Caussin, Mike | 83 | TE | 6-05 | 242 | 24 | 1 | UDFA (Jaguars-10) | James Madison Dukes |
| Corto, Jon | 33 | S | 6-00 | 208 | 28 | 4 | UDFA (Bills-07) | Sacred Heart Pioneers |
| Easley, Marcus | 81 | WR | 6-02 | 216 | 24 | 2 | D4 107th (Bills-10) | Connecticut Huskies |
| Hall, Bruce | 36 | RB | 5-11 | 205 | 26 | 1 | UDFA (Bills-08) | Mississippi Rebels |
| Jackson, Fred | 22 | RB | 6-01 | 210 | 30 | 5 | UDFA (Bills-06) | Coe College Kohawks |
| Jones, Donald | 19 | WR | 6-00 | 214 | 24 | 2 | UDFA (Bills-10) | Youngstown State Penguins |
| Lindell, Rian | 9 | K | 6-03 | 235 | 35 | 12 | UDFA (Cowboys-00) | Washington State Cougars |
| McGee, Terrence | 24 | CB | 5-09 | 201 | 31 | 9 | D4 111th (Bills-03) | Northwestern State (La.) Demons |
| Merriman, Shawne | 56 | OLB | 6-04 | 253 | 27 | 7 | D1 12th (Chargers-05) | Maryland Terrapins |
| Parrish, Roscoe | 11 | WR | 5-10 | 168 | 29 | 7 | D2 55th (Bills-05) | Miami (Fla.) Hurricanes |
| Rayner, Dave | 5 | K | 6-02 | 210 | 29 | 5 | D6 202nd (Colts-05) | Michigan State Spartans |
| Smith, Lee | 85 | TE | 6-06 | 269 | 24 | R | D5 159th (Patriots-11) | Marshall Thundering Herd |
| Torbor, Reggie | 53 | ILB | 6-02 | 250 | 31 | 8 | D4 97th (Giants-04) | Auburn Tigers |
| Troup, Torrell | 96 | DT | 6-03 | 314 | 23 | 2 | D2 41st (Bills-10) | UCF Golden Knights |
| White, Chris | 51 | ILB | 6-03 | 244 | 23 | R | D6 169th (Bills-11) | Mississippi State Bulldogs |
| Williams, Kyle | 95 | DT | 6-01 | 295 | 28 | 6 | D5 134th (Bills-06) | LSU Tigers |
| Wood, Eric | 70 | C | 6-04 | 304 | 25 | 3 | D1 28th (Bills-09) | Louisville Cardinals |
| Reserve - Future | ||||||||
| Name | No. | Pos. | Ht. | Wt. | Age | Exp. | League Entry | College |
| Clowney, David | WR | 6-00 | 188 | 26 | 4 | D5 157th (Packers-07) | Virginia Tech Hokies | |
| Eddins, Robert | 48 | OLB | 6-03 | 248 | 23 | R | UDFA (Bills-11) | Ball State Cardinals |
| McKillop, Scott | ILB | 6-01 | 244 | 25 | 3 | D5 146th (49ers-09) | Pittsburgh Panthers | |
| Miller, Prince | 44 | CB | 5-08 | 198 | 24 | 2 | UDFA (Ravens-10) | Georgia Bulldogs |
| Ross, Jay | 93 | DE | 6-03 | 302 | 24 | 1 | UDFA (Saints-10) | East Carolina Pirates |
| Vermiglio, Jake | 62 | OT | 6-05 | 329 | 24 | R | UDFA (Cardinals-11) | North Carolina State Wolfpack |
| Williams, Keith | 68 | OG | 6-05 | 312 | 23 | R | D6 196th (Steelers-11) | Nebraska Cornhuskers |